The transcription factor PR domain containing 16 (PRDM16) was found to be downregulated in lung adenocarcinomas, which represses the transcription of Mucin‐4 (MUC4), one of the regulators of epithelial‐to‐mesenchymal transition (EMT) process of cancer cells.38 Here, PRDM16 is linked to lung adenocarcinoma.