As shown in Table 3, fatigue (physical, mental and overall), serum albumin, sleep disorders, vitality, anxiety, depression, compliance with liquid intake recommendations, compliance with iron intake recommendations, self-monitoring disease, maintenance of personal health, complications, pain (anywhere in the body) and appetite significantly varied in the IG (P=0.000), but not in the CG (P>0.05), after the intervention. This evidence concerns the gene ALB and depressive disorder.