However, some studies have reported that different 5-HT receptors are involved in the mechanisms of anorexia and nausea and vomiting, as the role of 5-HT2B and 5-HT2C receptors was shown to be more critical than that of the 5-HT and 5-HT3 in anorexia [82,83], whereas the opposite has been reported in nausea and vomiting [70]. Here, HTR5A is linked to Anorexia.