TNF and COVID-19: Gaurav et al. reported the multi-therapeutic use of two Indian traditional medicinal plants such as Boerhaavia diffusa and Tinospora cordifolia, in the regulation of several pathways such as signaling to interleukins, response to the inorganic substances, TNF signaling pathway, lipid localization, regulation of defense response, RAS and bradykinin pathway in COVID-19, circulatory system process, cellular response to nitrogen compounds, etc. [33].