The prevalence of low, medium, and high risks of osteoporosis was significantly different in some variables in the groups of socio-demographics (gender, education level, marital status, and medication payment ability); the clinical parameters (rheumatoid arthritis, waist circumference, and diuretic usage); the biochemical parameters (level of serum albumin); and the health literacy and digital health diet literacy (p < 0.05). The gene discussed is ALB; the disease is osteoporosis.