AKT1 and cancer: Acting as oncomirs, milk-derived miR-21 and miR-155 have been related to breast cancer progression, enhancing tamoxifen resistance, metastasis formation, and worse prognosis [35], while miR-125b is involved in prostate xenograft cancer by targeting tumorigenic pathways, as p53, PI3K/AKT/mTORC1, ERBB2, and Wnt [36,37].