The primary endpoint was the difference in the postprandial glucose response, secondary endpoints were changes in the insulin, GLP-1, and GIP responses; insulin sensitivity, evaluated using the Matsuda index; insulin resistance, evaluated using an index obtained by multiplying the glucose area under the curve (AUC) and the AUC of insulin over 2 h (AUCins×glu); the homeostatic model assessment of insulin resistance index (HOMA-IR) and homeostasis model assessment β cell function (HOMA-β). This evidence concerns the gene GIP and Insulin resistance.