PTGS1 and multiple sclerosis: Compared, however, to the results of the same individuals before and after the institution of dietary therapy, a significantly impaired expression was noted of other proinflammatory enzymes, i.e., cyclooxygenase 1 (COX-1) and cyclooxygenase 2 (COX-2), and an inverse correlation was observed between the expression of proinflammatory genes and patients’ quality of life in the Multiple Sclerosis Quality of Life-54 (MSQOL-54) scale [210].