PPARA and metabolic dysfunction-associated steatotic liver disease: As shown in Figure 4A, D-NAFLD rats displayed increased levels of adipogenic genes including SREBP1c, FASN, and CD36 molecule (thrombospondin receptor) (CD36), but decreased FAO-associated genes, including Peroxisome proliferator activated receptor α (PPARα) and Carnitine palmitoyltransferase-1 (CPT1).