Chronic H. pylori infection induces excessive and chronic production of pro-inflammatory cytokines, such as IL1B (interleukin 1 beta), IL6 (interleukin 6), CXCL8 (C-X-C motif chemokine ligand 8), which are thought to promote the development and progression of GC [14]. This evidence concerns the gene CXCL8 and gastric cancer.