Edelfosine induces caspase- and mitochondrial-mediated apoptosis in pancreatic cancer cells via stress responses, with participation of the endoplasmic reticulum and caspase-4 and c-Jun (the name Jun comes from the Japanese translation of the number 17 “ju-nana”) NH2-terminal kinase activation [6]. This evidence concerns the gene JUN and familial pancreatic carcinoma.