The pathways mainly involved were Pathways in Cancer, PI3K-Akt signaling pathway, Chemical carcinogenesis-receptor activation, Endocrine resistance, Neuroactive ligand-receptor interaction, Lipid and atherosclerosis, cAMP signaling pathway, Progesterone-mediated oocyte maturation, Serotonergic synapse, Notch signaling pathway, and so on (Figure 12). Here, AKT1 is linked to atherosclerosis.