It can be seen from Table 2 that there are 20 common saponin components in the RG-NBE and SGD-NBE, which mainly consist of Rg1, Re, Rg3, Rb1, etc. Recent reports have shown that ginsenosides modify skin physiology and mitigate skin disorders such as photo-ageing and hyperpigmentation. The gene discussed is RB1; the disease is skin disorder.