Dioscin—a diosgenin glycoside—induced apoptosis in human ovarian cancer SKOV-3 cells in a dose-dependent manner, increased caspase-3 and -9 activity, the protein expression of Bax, and suppressed cell viability by regulating the PI3K/AKT/MAPK signaling pathways [47]. The gene discussed is CASP3; the disease is ovarian cancer.