The univariate analysis indicated that patients with AKI had a higher frequency of hypertension (odds ratio, OR = 11.42, 95% CI: 1.15–113, p = 0.037), and EGF > 4600 pg/mL was associated with a lower risk of AKI (OR = 0.05, 95% CI: 0.008–0.40; p = 0.004). The gene discussed is EGF; the disease is Hypertension.