VSIR and cancer: The lymphocyte activation gene-3 (LAG3), the pathway of the T-cell immunoglobulin and the ITIM domain, the T-cell immunoglobulin mucin-3 (TIM-3), and the V tomorrow-containing IG suppressor of T-cell activation (VISTA) are some examples of the alternative immune checkpoint that cancer cells use [8,147,148,149,150,151,152,153].