In colorectal cancer cells, epigallocatechin-3-gallate, a polyphenol phytochemical, was discovered to inhibit the expression of Notch, BMI1, and EZH2 with an upregulation of the expression of miR-145, miR-34a, and miR-200c, thus reducing tumor growth [38]. The gene discussed is EZH2; the disease is neoplasm.