TNF and colitis: Therefore, to examine whether MLN DCs from Yeti/CD1d KO mice show proinflammatory phenotypes during DSS-induced colitis, we compared proinflammatory cytokine production (i.e., IL12, TNFα, and IL6) by both splenic DCs and MLN DCs from WT, Yeti, CD1d KO, and Yeti/CD1d KO mice during DSS treatment.