Papila and colleagues compared serum values of NF-ƙB, PTX-3, IL-6, CRP, TNF-α, and sTRAIL (soluble TNF-related apoptosis-inducing ligand) and PCT (procalcitonin) in 40 individuals diagnosed with breast cancer, 40 with colon cancer, and 30 health controls [97]. This evidence concerns the gene TNF and malignant colon neoplasm.