PTX3 and Cirrhosis: PTX-3 is associated with many non-malignant conditions (e.g., asthma, hepatic cirrhosis, atherosclerosis, rheumatoid arthritis, systemic lupus erythematosus, sepsis, acute kidney injury, chronic kidney disease, stroke), but also it is overexpressed in various types of tumors (e.g., prostate/breast/lung/hepatic cancer, glioma) [31].