Nevertheless, the study conducted by Goulart and colleagues demonstrated that PTX-3 serum levels are correlated with PTX-3 tissue levels in patients with pancreatic carcinoma and PTX-3 is presented as a differentiation biomarker between pancreatic cancer and other diseases (chronic pancreatitis and intraductal papillary mucinous neoplasm) [122]. This evidence concerns the gene PTX3 and pancreatic neoplasm.