Hutchinson–Gilford progeria syndrome (HGPS; OMIM #176670) is an extremely rare (estimated prevalence: 1/20,000,000) autosomal dominant disorder caused by mutations in the LMNA (lamin A) gene resulting in an aberrantly spliced protein product termed ‘progerin’ [60]. This evidence concerns the gene LMNA and Hutchinson-Gilford progeria syndrome.