There were 3.75% of the interactors which were common to both pathways of cancer and CRC, namely, PIK3CD, AKT1, AKT3, BAX, BIRC5, GSK3B, MAPK1, MYC, PIK3CG, PIK3R2, RAC1, RAF1, RHOA, SMAD2, SMAD4, TGFB1, and TGFBR1. Here, AKT1 is linked to cancer.