The distributions of CD4 rs1992452, CD4 rs951818, and LAG3 rs878049 genotypes and allelic frequencies were similar between “relapsing–remitting”, “secondary progressive”, and “primary progressive” clinical evolutive subtypes of MS and controls, except for a significantly higher frequency of rs870849CC genotype and rs870849C allelic variant in patients with “relapsing–remitting” compared with those with “primary progressive” MS, which disappeared after correction for multiple comparisons (p = 0.019, Pc = 0.171 for genotypes, and p = 0.023, PC = 0.069 for alleles) (Table 5). The gene discussed is CD4; the disease is myeloid sarcoma.