Following the silencing of TERC in cancer cells such as HCT116 [142], HeLa ([143], and murine melanoma [144], similar results have been observed: downregulation of genes involved in proliferation (cyclins, oncogenes, DNA repair proteins, chromatin regulators, transcription factors, ribosomal genes) and in the glycolytic pathway, and upregulation of genes involved in differentiation (Table S2 in Supplementary Material). Here, TERC is linked to cancer.