CPD and xeroderma pigmentosum: Hence, the combination of CPD photolyases and conventional sunscreen has been used as an adjuvant therapy in patients with actinic keratosis (AK), non-melanoma skin cancer (NMSC), and xeroderma pigmentosum (XP), improving visible and cancerous lesions and protecting against the appearance of new lesions [28,35,36,37,38].