ACE2 and viral infectious disease: In a similar study by analysis of the 25 amino acids of ACE2 interacting with SARS-CoV-2 spike protein, the marine mammals living in Italian coastal waters are supposed to have medium to high susceptibility to SARS-CoV-2 infection, and the immunohistochemistry for ACE2 protein distribution in lung tissues of cetacean species suggests that ACE2 is expressed in alveolar and bronchial epithelium, supporting viral infection potentials [79].