The cold temperature of the Antarctic ocean may favor the viability of SARS-CoV-2 for an extended period of time, and the predicted high binding affinity of ACE2 of Antarctic minke whales and killer whales, and the medium affinity of the ACE2 of sperm whales, suggest the infection potentials of these Antarctic mammals by SARS-CoV-2 [76,77]. Here, ACE2 is linked to infection.