KCNT1 and epilepsy: The analysis of correlation between the symptoms caused by the different KCNT1 mutations and the properties of KCNT1 current suggests for the first time, that KCNT1 Po at resting membrane potential is a strong predictor of the severity of KCNT1-related epilepsy and supports the notion that pathogenicity of KCNT1 mutations is caused by their effects on the resting K+ membrane conductance, rather than the current amplitude at positive potentials.