In agreement with the previous studies, SZU251 + MUC1 caused a rapid induction of common cytokines such as IL6, TNFα and IFNγ in mouse BMDCs and spleen lymphocytes in vitro (Figure 2A,B), favoring Th1-mediated immune responses and cytotoxic T cells acting on cancer cells [22]. The gene discussed is TNF; the disease is cancer.