There are numerous studies reporting high expression levels of SIRT1 in cancers, such as breast cancer [86], colorectal adenocarcinoma [87], hepatocellular carcinoma [88], soft tissue sarcomas [89], prostate cancer [90], ovarian and cervical cancers [91], lymphoma [92], and GC [77,93]. The gene discussed is SIRT1; the disease is gastric cancer.