Among the proteins with a reduced level of expression in the hippocampal area, two isoforms of the stathmin protein (STMN) were identified for both models, the STMN1 with pI 5.6 and PM 17158 and the second with pI 5.3 and PM 17406, whose high specificity of binding with tubulin determines a role of primary importance in the developmental biology of the cerebral system, in particular in the formation of the axon, in cell proliferation (formation of the mitotic spindle) and in the more interesting role of a response to viral infections. This evidence concerns the gene STMN1 and viral infectious disease.