The interplay between macrophages and MuSCs was also studied in Duchenne Muscular Dystrophy (DMD), a primary myopathy caused by the loss of functional dystrophin protein, where sustained myogenic activation of MuSCs can be alleviated by M1-to-M2 induction via IL-10 administration by reducing the activation of the M1 phenotype [51]. Here, DMD is linked to Duchenne muscular dystrophy.