Additionally, they found that the genotypes of the stromelysin-1 genes (5A-1171/6A and MMP-3 polymorphisms) may be effective in detecting the hereditary risk of myocardial infarction and, therefore, may aid in primary prevention, in addition to the connexin-37 and plasminogen-activator inhibitor type 1 genes’ implications in MI [26]. This evidence concerns the gene MMP3 and myocardial infarction.