Concerning responding T-cells, at T0, a lower percentage of responding T-cells in PLWH with <200 cells/μL compared to PLWH with >200 cells/μL was observed (CD4: p = 0.0331; CD8: p = 0.0055) as well as compared to HD (CD4: p = 0.0295; CD8: p = 0.0056) (Figure 2D). The gene discussed is CD8A; the disease is Huntington disease.