We recently discovered a seven-gene (ABCC4, CCL19, CD27, DAG1, FUT7, SLC39A8, and ZNF71) signature that accurately predicts the risk of recurrence/metastasis in retrospective analyses of 1500 early-stage NSCLC patients for all histological subtypes, including clinical trials [14,15]. The gene discussed is DAG1; the disease is non-small cell lung carcinoma.