TGFB1 and pulmonary fibrosis: In contrast, FGF-1 suppresses the TGF-β-stimulated differentiation of myofibroblasts and EMT through proteasomal degradation of TGF-β receptors [229], and a significant decrease in FGF-10 expression in AEC precursors in patients with progressing pulmonary fibrosis was detected [148], which suggests the dual role of FGFs in fibrogenesis.