The four major cell types of GBM are shown in Figure 3C: tumor cells (PTPRZ1, OLIG2, PDGFRA, DLL3, AQP4, and CLU), immune cells (PTPRC, P2RY12, CD163, CXCL1, FCGR3B, and FCN1), proliferation cells (MKI67), and normal cells (MOG). This evidence concerns the gene DLL3 and neoplasm.