The four major cell types of GBM are shown in Figure 3C: tumor cells (PTPRZ1, OLIG2, PDGFRA, DLL3, AQP4, and CLU), immune cells (PTPRC, P2RY12, CD163, CXCL1, FCGR3B, and FCN1), proliferation cells (MKI67), and normal cells (MOG). Here, AQP4 is linked to glioblastoma.