SPO11 and cancer: The other (or the same) route are the cycles of so-called mitotic slippage (reversal of metaphase arrest after DNA re-replication, not accomplishing mitosis) expressing the meiotic proteins (DMC1, SPO11, MOS, REC8, STAG3, SCYP1, SCYP3, POU5F1) observed in vitro on the irradiated p53-mutant lymphoma cell lines [12,27], and doxorubicin-treated basal breast cancer cell line [81] and some meiotic genes in luminal MCF7 cancer after TOPO I inhibitor [84].