AHR and colonic neoplasm: However, AHR expression appears to be deregulated in patients with colon cancer according to the cancer genome atlas (TCGA) database (https://xenabrowser.net/, accessed on 25 January 2021), although its endogenous activation by ligands from the diet such as Indole-3-acetic acid (IAA) or β-naphthoflavone (βNF) prevents colon tumorigenesis [146].