For instance, Giordano M. et al. [162] found that diabetic patients with stroke showed a larger expression of miRNA-195-5p and miRNA-451a and a lower expression of VEGF-A levels in comparison to non-diabetic patients, probably reflecting a different risk-profile of diabetic patients who show a particularly complex interplay of several inflammatory and metabolic aspects, strongly affecting the cardio-vascular system [163,164]. This evidence concerns the gene VEGFA and stroke disorder.