TNF and acute respiratory distress syndrome: In addition, the experimental results from Lee et al. demonstrated that MH exerts an anti-inflammatory effect by suppressing the secretion of NO and the expression of iNOS in lipopolysaccharide (LPS)-stimulated RAW264.7 macrophages, and it exerts protective effects in mice with LPS-induced acute respiratory distress syndrome (ARDS) by inhibiting the secretion of TNF-α/IL-1β and the expression of iNOS [33,34].