The increased expression of TRPM6 and TRPM7 proteins in disease conditions was confirmed by an enzyme-linked immunosorbent assay (ELISA) as shown in Figure 8D. The detected TRPM6 and TRPM7 protein concentrations for human tissue homogenates in SR (non-IHD) were 53.1 ± 6.64 pg/mL and 169.4 ± 8.45 pg/mL, respectively (n = 11); for human tissue homogenates with AF, they were 84.8 ± 11.29 pg/mL and 245.1 ± 24.07 pg/mL, respectively (n = 9; p < 0.05 vs. SR); for human tissue homogenates with IHD, they were 135.9 ± 7.18 pg/mL and 392.6 ± 29.77 pg/mL, respectively (n = 12). Here, TRPM6 is linked to atrial fibrillation.