ALB and liver dysplastic nodule: In another cohort of 76 T2D-DN patients based in China, Jiang et al. [51] showed that, following administration of multispecies probiotic supplements containing 3.2 × 109 CFU/d Bifidobacterium bifidum, Lactobacillus acidophilus, and Streptococcus thermophilus, urine Alb/Cr decreased from 101.60 ± 22.17 to 67.53 ± 20.11 mg/g, compared to significantly different (p < 0.05) end-of-trial mean of 87.71 ± 23.01 mg/g in the control group which had a similar baseline value.