The strong association of DGCR8 downregulation in follicular-patterned carcinomas is also present in FTC, where underexpression is again present in most of the cases, 66.7% (4 out 6) and with significant differences (paired t-test, p < 0.05), Figure 2C. An interesting case in this series, was a multifocal PTC in a patient with two subtypes, a cPTC and a FV-PTC with Q61R NRAS mutation that in accordance with the previous findings, presented DGCR8 overexpression and underexpression, respectively, in the different components. Here, DGCR8 is linked to thyroid cancer, nonmedullary, 2.