It has been reported earlier that STIM1 acts as a negative regulator of endogenous or overexpressed L-type calcium channels upon ER calcium store depletion in arterial smooth muscle cells (A7r5 VSMCs), cortical neurons, Jurkat T cells, HEK293 cells, and neuroblastoma Neuro2a [36,37]. Here, STIM1 is linked to neuroblastoma.