The SLC2A family of glucose transporters was also strongly implicated in HD, with GLUT1 (SLC2A1) and GLUT3 (SLC2A3) expression shown to be 3- and 4-fold decreased in late stage patients [152], while an increase in GLUT4 (SLC2A4) expression was seen in a different study [153]. This evidence concerns the gene SLC2A1 and Huntington disease.