Although host-derived SMS-2 was shown to be recruited to the chlamydial inclusions [11], it was recently reported that a double knock-out of SGMS1 and SGMS2 (which encode SMS-1 and SMS-2, respectively) in human cervical carcinoma-derived HeLa cells (hereafter referred to as HeLa∆SMS-1/2 cells) did not affect chlamydial infection or proliferation [10]. Here, SGMS1 is linked to cervical carcinoma.