Recently, microglial Kv1.3 has been reported to be related to a variety of neurological diseases in which neuroinflammation is involved, such as Parkinson’s disease (PD), Alzheimer’s disease (AD), and middle cerebral artery occlusion/reperfusion (MCAO/R) [25,26,27,28]. The gene discussed is KCNA3; the disease is Alzheimer disease.