On the other hand, as IL-10 is thought to be a key suppressor of the immune response [42], the observed upregulation of this cytokine in both timepoints in our study might also be a compensatory protective mechanism in response to the overexpression of IL6 and IL18, i.e., both cytokines with pro-inflammatory actions found in our hyperglycemic GDM women during and after pregnancy, and this possibility needs to be addressed by future studies. The gene discussed is IL6; the disease is gestational diabetes.