Hence, miR-29c-3p may promote intestinal inflammation by targeting leukemia inhibitory factor (LIF) in ulcerative colitis and, through targeting the transcription factor forkhead box protein O3 (FOXO3A), may ameliorate inflammatory damage of cells by NOD-, LRR- and pyrin domain-containing protein 3 (NLRP3) inflammasome inhibition [197,198,199]. This evidence concerns the gene FOXO3 and ulcerative colitis.