In levamisole-adulterated cocaine intoxications [33,44,45,46,47,54,57,58,59,60,61,62] the p- or c-ANCA positivity was associated with Cocaine Induced Midline Destructive Lesions (CIMDL) (n = 5) [44,57], vasculitis (n = 8) [33,47,58,59,60,61], membranous glomerulonephritis (n = 4) [58,62], pyoderma gangrenosum (n = 1) [54], neutropenia complicated with bowel necrosis (n = 1) [46], and cerebral white matter dysfunction (n = 1) [45]. Here, PRTN3 is linked to pyoderma gangrenosum.