MMP9 and age-related macular degeneration: A previous study that quantified MMP9 in the plasma of (a) controls, (b) patients with either large soft distinct drusen with pigmentary abnormalities, indistinct drusen or reticular drusen, or (c) NV AMD, reported values of 265 ng/mL, 659 ng/mL and 740 ng/mL, respectively, showing significantly elevated MMP9 in both early-intermediate AMD and NV groups vs. controls [19].